Topics covered:

Introduction, course objectives, laboratory assignments, electrical conductivity and permitivity of tissue, biological effects of non-ionizing electromagnetic fields and how these electric and magnetic fields are coupled to your body. Safety standards

The origin of natural biopotentials: neuromuscular structure, AP origin and propagation

The building blocks of a biomedical instrument: transducers or electrodes, the instrumentation amplifier, isolation amplifier, filters, and data storage.

Electrode design for recording and stimulation: How to measure the electrode equivalent circuit

Transducers: pressure, temperature, displacement, gases, electrolytes

Transducers: optical, immunological, magnetic, flowmeters

How to build a good differential amplifier and isolate its power supply from earth ground (required for any clinical measurement) and implement analog filters

A to D, D to A, the sampling theorem, resolution, precision, data storage structures, sources of error, and error (distortion) analysis

Design of a virtual instrument using LABVIEW

How to measure EMG, EKG, EEG, EOG, ERG, and GSR and what do they mean

Evoked potentials: Measurement and analysis and how are they useful

Biomedical signal processing: power spectrum, joint time-frequency analysis, graphical representation of data, and data mining

Microprocessors and microcontrollers in biomedical instrumentation

Cardiovascular Measurements: EKG, auscultation, echocardiography, the Swan-Ganz catheter, pacemakers

The neuro-ICU and neurodiagnostics

Vision: Diagnostics and surgery

Vision: the visual prosthesis

MRI, CT, PET, advanced imaging, and therapeutic radiology.

Vestibulocochlear system, audiology, hearing aids, cochlear prosthesis

Laser-tissue interaction: the laser as a therapeutic tool

Spectroscopy, OCT, and the laser as a diagnostic tool

Thermal imaging, electrosurgery, electrocautery, and endoscopic surgery

Microscopy, image processing and machine vision (automated cell recognition and counting)

Human kinematics, biomechanics, and neuroprosthesis design

Respiratory physiology, blood gases, and ventilation

Bioinstrumentation in anesthesia

Cryogenics, tissue preservation and tissue transplantation, biomaterials

Instrumentation in obstetrics and gynecology, in vitro fertilization; diagnostic ultrasound and stem cell research

MEMS and nanotechnology (with DNA sequencing application)